1.Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease

Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y.

Signal Transduct Target Ther. 2023 Jun 16;8(1):229.

2.Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice

Liu H, Ju A, Dong X, Luo Z, Tang J, Ma B, Fu Y, Luo Y.

J Transl Med. 2023 Feb 6;21(1):89.

3.NAD⁺ supplementation limits triple-negative breast cancer metastasis via SIRT1-P66Shc signaling

Jiang Y, Luo Z, Gong Y, Fu Y, Luo Y.

Oncogene. 2023 Mar;42(11):808-824.

4.Extracellular Heat Shock Protein-90 (eHsp90): Everything You Need to Know

Jay D, Luo Y, Li W.

Biomolecules. 2022 Jun 29;12(7):911.

5.Antigen Peptide Transporter 1 (TAP1) Promotes Resistance to MEK Inhibitors in Pancreatic Cancers

Li B, Feng Y, Hou Q, Fu Y, Luo Y.

Int J Mol Sci. 2022 Jun 28;23(13):7168.

6.Suppression of CCT3 Inhibits Tumor Progression by Impairing ATP Production and Cytoplasmic Translation in Lung Adenocarcinoma

Chen S, Tian Y, Ju A, Li B, Fu Y, Luo Y.

Int J Mol Sci. 2022 Apr 2;23(7):3983.

7.TP53 mutations upregulate RCP expression via Sp1/3 to drive lung cancer progression.

Wang C, Zhang S, Ma B, Fu Y, Luo Y

Oncogene. 2022 Apr;41(16):2357-2371.

8.Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice

Tang J, Ju A, Li B, Zhang S, Gong Y, Ma B, Jiang Y, Liu H, Fu Y, Luo Y.

Biomolecules. 2021 Aug 12;11(8):1191.

9.Pyroptosis-Related Gene Signatures Can Robustly Diagnose Skin Cutaneous Melanoma and Predict the Prognosis

Ju A, Tang J, Chen S, Fu Y, Luo Y.

Front Oncol. 2021 Jul 13;11:709077.

10.Extracellular Hsp90α Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer

Hou Q, Chen S, An Q, Li B, Fu Y, Luo Y.

Int J Mol Sci. 2021 Jul 20;22(14):7747.

11.Combination of MAPK inhibition with photothermal therapy synergistically augments the anti-tumor efficacy of immune checkpoint blockade

Liu X, Feng Y, Xu J, Shi Y, Yang J, Zhang R, Song J, Bai X, Wu X, Bao Y, Luo Y, Li H, Chai L, Gong C, Wang Y, Chen B, Hu J, Fu Y, Luo Y, Zhang H, Shi H.

J Control Release. 2021 Apr 10;332:194-209.

12.Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion

Zhang S, Wang C, Ma B, Xu M, Xu S, Liu J, Tian Y, Fu Y, Luo Y.

Cell Rep. 2020 Jul 7;32(1):107879.

13.Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway

Wang C, Zhang S, Liu J, Tian Y, Ma B, Xu S, Fu Y, Luo Y.

Cell Rep. 2020 Feb 11;30(6):1780-1797.e6.

14.Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner

Gong Y, Wang C, Jiang Y, Zhang S, Feng S, Fu Y, Luo Y.

Cells. 2020 Jan 7;9(1):144.

15.Pharmacokinetics of PEGylated recombinant human endostatin in rhesus monkeys

Guo L, Li Z, Xu B, Yu M, Fu Y, Liu L, Wang J, Luo Y.

Life Sci. 2019 Dec 1;238:116967.

16.A novel pan-cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic

Liu W, Li J, Zhang P, Hou Q, Feng S, Liu L, Cui D, Shi H, Fu Y, Luo Y.

Cancer Sci. 2019 Sep;110(9):2941-2959.

17.Biophysical and biological characterization of PEGylated recombinant human endostatin

Guo L, Xu B, Zhou D, Chang G, Fu Y, Liu L, Luo Y.

Clin Exp Pharmacol Physiol. 2019 Oct;46(10):920-927.

18.Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1

Tian Y, Wang C, Chen S, Liu J, Fu Y, Luo Y.

J Cell Sci. 2019 Jul 31;132(15):jcs228213.

19.Lysyl Oxidase-Like Protein 2 Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer

Wang C, Xu S, Tian Y, Ju A, Hou Q, Liu J, Fu Y, Luo Y.

Neoplasia. 2019 Apr;21(4):413-427.

 20.CXCR7 promotes melanoma tumorigenesis via Src kinase signaling

Xu S, Tang J, Wang C, Liu J, Fu Y, Luo Y.

Cell Death Dis. 2019 Feb 25;10(3):191.

21.Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E

Ma X, Li B, Liu J, Fu Y, Luo Y.

J Exp Clin Cancer Res. 2019 Feb 11;38(1):66.

22.Quality, bioactivity study, and preclinical acute toxicity, safety pharmacology evaluation of PEGylated recombinant human endostatin (M₂ES)

Guo L, Geng X, Liu L, Miao Y, Lin Z, Yu M, Fu Y, Liu L, Li B, Luo Y.

J Biochem Mol Toxicol. 2019 Mar;33(3):e22257.

23.High expression of CCR5 in melanoma enhances epithelial-mesenchymal transition and metastasis via TGFβ1

Liu J, Wang C, Ma X, Tian Y, Wang C, Fu Y, Luo Y.

J Pathol. 2019 Apr;247(4):481-493.

24.A pre-clinical safety study of PEGylated recombinant human endostatin (M₂ES) in Sprague Dawley rats

Geng X, Guo L, Liu L, Wang C, Peng Q, Qi W, Sun L, Liu X, Miao Y, Lin Z, Fu Y, Luo Y, Li B.

Regul Toxicol Pharmacol. 2018 Jun;95:190-197.

25.Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells

Liu G, Feng S, Jia L, Wang C, Fu Y, Luo Y.

Oncogene. 2018 Mar;37(11):1519-1533.

26.Plasma Heat Shock Protein 90alpha as a Biomarker for the Diagnosis of Liver Cancer: An Official, Large-scale, and Multicenter Clinical Trial

Fu Y, Xu X, Huang D, Cui D, Liu L, Liu J, He Z, Liu J, Zheng S, Luo Y.

EBioMedicine. 2017 Oct;24:56-63.

27.E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer

Xu M, Zhang S, Jia L, Wang S, Liu J, Ma X, Wang C, Fu Y, Luo Y.

Front Pharmacol. 2017 Aug 9;8:532.

28.Endostatin sensitizes p53-deficient non-small-cell lung cancer to genotoxic chemotherapy by targeting DNA-dependent protein kinase catalytic subunit

Jia L, Lu XA, Liu G, Wang S, Xu M, Tian Y, Zhang S, Fu Y, Luo Y.

J Pathol. 2017 Oct;243(2):255-266.

29.Adrenomedullin promotes the growth of pancreatic ductal adenocarcinoma through recruitment of myelomonocytic cells

Xu M, Qi F, Zhang S, Ma X, Wang S, Wang C, Fu Y, Luo Y.

Oncotarget. 2016 Aug 23;7(34):55043-55056.  

30.Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog

Wang S, Fu Y, Luo Y.

Chin J Cancer. 2016 Jan 20;35:14.

31.Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p

He T, Qi F, Jia L, Wang S, Wang C, Song N, Fu Y, Li L, Luo Y.

Cancer Lett. 2015 Nov 1;368(1):115-125.

32.Pharmacokinetics of PEGylated recombinant human endostatin (M2ES) in rats

Li ZG, Jia L, Guo LF, Yu M, Sun X, Nie W, Fu Y, Rao CM, Wang JZ, Luo YZ.

Acta Pharmacol Sin. 2015 Jul;36(7):847-54.

33.Specific chemotherapeutic agents induce metastatic behaviour through stromal- and tumour-derived cytokine and angiogenic factor signalling

Liu G, Chen Y, Qi F, Jia L, Lu XA, He T, Fu Y, Li L, Luo Y.

J Pathol. 2015 Oct;237(2):190-202.

34.High expression of small GTPase Rab3D promotes cancer progression and metastasis

Yang J, Liu W, Lu X, Fu Y, Li L, Luo Y.

Oncotarget. 2015 May 10;6(13):11125-38.

35.The miR-30 Family Inhibits Pulmonary Vascular Hyperpermeability in the Premetastatic Phase by Direct Targeting of Skp2

Qi F, He T, Jia L, Song N, Guo L, Ma X, Wang C, Xu M, Fu Y, Li L, Luo Y.

Clin Cancer Res. 2015 Jul 1;21(13):3071-80.

36.Endostatin has ATPase activity, which mediates its antiangiogenic and antitumor activities

Wang S, Lu XA, Liu P, Fu Y, Jia L, Zhan S, Luo Y.

Mol Cancer Ther. 2015 May;14(5):1192-201.

37.Nuclear-translocated endostatin downregulates hypoxia inducible factor-1α activation through interfering with Zn(II) homeostasis

Guo L, Chen Y, He T, Qi F, Liu G, Fu Y, Rao C, Wang J, Luo Y.

Mol Med Rep. 2015 May;11(5):3473-80.

38.Endostatin Prevents Dietary-Induced Obesity by Inhibiting Adipogenesis and Angiogenesis

Wang H, Chen Y, Lu XA, Liu G, Fu Y, Luo Y.

Diabetes. 2015 Jul;64(7):2442-56.

39.Endostatin inhibits the tumorigenesis of hemangioendothelioma via downregulation of CXCL1

Guo L, Song N, He T, Qi F, Zheng S, Xu XG, Fu Y, Chen HD, Luo Y.

Mol Carcinog. 2015 Nov;54(11):1340-53.

40.Phase I trial of M₂ES, a novel polyethylene glycosylated recombinant human endostatin, plus gemcitabine in advanced pancreatic cancer

Chen Y, DU Y, Li P, Wu F, Fu Y, Li Z, Luo Y.

Mol Clin Oncol. 2014 Jul;2(4):586-590.

41.PLCγ1-PKCγ signaling-mediated Hsp90α plasma membrane translocation facilitates tumor metastasis

Yang J, Song X, Chen Y, Lu XA, Fu Y, Luo Y.

Traffic. 2014 Aug;15(8):861-78.

42.Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys

Guo L, Geng X, Chen Y, Qi F, Liu L, Miao Y, Lin Z, Yu M, Li Z, Fu Y, Li B, Luo Y.

Regul Toxicol Pharmacol. 2014 Aug;69(3):512-23.

43.Pre-clinical toxicokinetics and safety study of M2ES, a PEGylated recombinant human endostatin, in rhesus monkeys

Guo L, Geng X, Chen Y, Qi F, Liu L, Miao Y, Lin Z, Yu M, Li Z, Fu Y, Li B, Luo Y.

Regul Toxicol Pharmacol. 2014 Aug;69(3):512-23.

44.MicroRNA-542-3p inhibits tumour angiogenesis by targeting angiopoietin-2

He T, Qi F, Jia L, Wang S, Song N, Guo L, Fu Y, Luo Y.

J Pathol. 2014 Apr;232(5):499-508.

45.Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis

Jiang WG, Lu XA, Shang BY, Fu Y, Zhang SH, Zhou D, Li L, Li Y, Luo Y, Zhen YS.

BMC Cancer. 2013 Oct 15;13:479.

46.The regulatory mechanism of a client kinase controlling its own release from Hsp90 chaperone machinery through phosphorylation

Lu XA, Wang X, Zhuo W, Jia L, Jiang Y, Fu Y, Luo Y.

Biochem J. 2014 Jan 1;457(1):171-83.

47.Prognostic significance of the combined score of endothelial expression of nucleolin and CD31 in surgically resected non-small cell lung cancer

Zhao H, Huang Y, Xue C, Chen Y, Hou X, Guo Y, Zhao L, Hu Zh, Huang Y, Luo Y, Zhang L.

PLoS One. 2013;8(1):e54674.